Duphalac contains the active ingredient lactulose. It is sometimes called by its generic name, lactulose syrup. Duphalac is used to treat constipation and helps to make bowel movements easier. It works by softening the stools and promoting regular bowel movements.
Duphalac costs between £25.48 and £41.1 per bottles. Depending on the size of the pack and the number of tablets inside (1 or 10 ml).
Duphalac contains lactulose as its active ingredient. Lactulose is a synthetic disaccharide formed from fructose and galactose. It specifically promotes bowel movements and alleviates constipation.
Duphalac is administered orally. It is available in a liquid solution form designed for ease of ingestion. Patients should follow the prescribed dosage instructions closely.
Duphalac is primarily indicated for the treatment of chronic constipation. It is also prescribed for hepatic encephalopathy, helping to reduce the production of ammonia in the intestines.
The initial dosage for adults with chronic constipation typically ranges from 15 to 45 ml per day. For maintenance, the usual dose ranges between 15 to 30 ml per day. Paediatric dosages vary based on age and specific medical recommendations.
Lactulose in Duphalac works by breaking down into acids in the colon. This process enhances osmotic pressure, drawing water into the bowels, thereby softening stools and promoting motility. Additionally, it reduces ammonia absorption in the gut.
Duphalac may interact with non-absorbable antibiotics, which can reduce its effectiveness. Patients taking other laxatives or medications impacting gastrointestinal motility should consult their physician for tailored advice.
Duphalac is contraindicated in individuals with galactosemia, a rare metabolic disorder. It should not be administered to patients experiencing intestinal blockages or hypersensitivity to lactulose or its components.
Store Duphalac below 25°C (77°F) in a tightly closed container. Do not freeze. Keep out of reach of children.
Duphalac is minimally absorbed in the gastrointestinal tract, allowing most of it to reach the colon intact. Its therapeutic effect begins within 24 to 48 hours after ingestion.
Common side effects include flatulence, abdominal cramps, and bloating. Less frequently, patients may experience electrolyte imbalance, diarrhea, or nausea.
For pregnant patients, Duphalac is generally considered safe. However, it is advisable to consult a healthcare provider. The same caution applies to lactating women and patients with preexisting gastrointestinal conditions.
Regular monitoring of bowel movement frequency and consistency is recommended. Blood ammonia levels should be measured in patients treated for hepatic encephalopathy.
In case of overdose, symptoms include severe diarrhea and electrolyte imbalance. Immediate medical attention is necessary, with supportive measures such as hydration and electrolyte management.
Advise patients to maintain adequate fluid intake while using Duphalac. Inform them about the onset of action and possible initial bloating. Encourage compliance with dietary and lifestyle changes to support therapy.
Duphalac is ready to use and should not be diluted unless prescribed. Shake the bottle well before each use, and measure the dose accurately using the provided measuring cup.
If a dose is missed, patients should take it as soon as remembered, unless it is close to the time for the next dose. Avoid doubling the dose to catch up.
Duphalac is supplied in bottles of various sizes, typically ranging from 200 ml to 1000 ml. The packaging includes a measuring cup for accurate dosing.
Duphalac is a cost-effective treatment for chronic constipation and hepatic encephalopathy, reducing the need for additional healthcare resources.
Duphalac is classified as an over-the-counter (OTC) medication in many regions, but prescription requirements may vary by country.
While specifically branded as Duphalac, lactulose is also available under various generic labels. The formulation and therapeutic effects remain consistent across brands.
Encourage patients to regularly monitor symptoms and report any significant changes to their healthcare provider. Advise against using Duphalac for conditions other than those prescribed.
Lactulose is a synthetic sugar, chemically represented as C12H22O11. It exhibits high solubility in water, enhancing its utility as a liquid medication.