Provigil

Provigil contains the active ingredient modafinil. It is also known by its generic name, modafinil, or the brand name Alertec. Provigil is used to help people stay awake and alert. It is often prescribed to treat sleep disorders like narcolepsy, sleep apnea, and shift work sleep disorder.

Price of Provigil

The general market rate for Provigil varies from £0.66 to £1.42 per pills. Determining factors include the size of the packaging and the potency of its components (30 or 360 mg).

Check price

Description

Medication Guide: Provigil

Brand Name

Provigil

Generic Name

Modafinil

Drug Class

CNS stimulants

Indications

Provigil is prescribed for the treatment of narcolepsy to improve wakefulness. It is also used for the management of obstructive sleep apnea (OSA) and shift work sleep disorder (SWSD).

Mechanism of Action

Provigil (modafinil) works by increasing the amount of dopamine in the brain by inhibiting the reuptake of dopamine into nerves. This promotes wakefulness in patients.

Dosage and Administration

The recommended dosage for narcolepsy and OSA is 200 mg once a day in the morning. For shift work sleep disorder, a 200 mg dose should be taken approximately one hour before the start of the work shift.

Dosage Adjustments

Patients with severe hepatic impairment should receive reduced dosages. The recommended dose is reduced to 100 mg once a day. It is also advised to monitor kidney functions and consider adjustments in patients with renal impairments.

Missed Dose

If a dose is missed, it should be taken as soon as possible. If it is close to the next dose, skip the missed dose and continue on the regular schedule. Do not double the dose to catch up.

Overdose Management

In case of overdose, standard supportive measures should be taken. Symptoms of overdose may include severe restlessness, confusion, and cardiovascular instability. Seek emergency medical help immediately.

Storage Instructions

Store Provigil at room temperature between 20°C to 25°C (68°F to 77°F). Protect from light and moisture. Keep out of reach of children and pets.

Drug Interactions

Provigil can interact with a variety of medications. Notable interactions include contraceptives, cyclosporine, and certain antidepressants. Patients should inform their healthcare provider of all medications they are currently taking.

Side Effects

Common side effects include insomnia, headache, dizziness, and nausea. Less common but serious side effects may include rash, allergic reactions, and psychiatric symptoms such as anxiety and depressive episodes.

Monitoring Parameters

Healthcare providers should monitor blood pressure, heart rate, and symptoms of psychiatric conditions. Liver function tests should be periodically performed in patients with hepatic conditions.

Use in Pregnancy

Provigil falls under Pregnancy Category C. It should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Healthcare providers should discuss risks and benefits with pregnant patients.

Breastfeeding Considerations

It is unknown if Provigil is excreted in human milk. Caution should be exercised when administered to nursing mothers. Discuss potential risks with a healthcare provider.

Use in Elderly

Elderly patients may be more susceptible to side effects such as dizziness and confusion. Dose adjustment may be required, and close monitoring is advised.

Substance Abuse Potential

Provigil has a potential for abuse and dependence. It is classified as a Schedule IV controlled substance. Monitor patients for signs of misuse and dependency.

Tapering Off

If discontinuation of Provigil is required, it is advised to taper the dose gradually under medical supervision to minimize withdrawal symptoms or exacerbation of the underlying condition.

Use with Alcohol

Patients are advised to avoid alcohol consumption while taking Provigil, as alcohol may increase the risk of adverse effects such as dizziness and impaired judgment.

Laboratory Test Alteration

Provigil can alter the results of some laboratory tests, such as liver enzyme levels. Inform healthcare providers about the use of Provigil before undergoing any medical tests.

Patient Counselling Points

Patients should be advised to take Provigil exactly as prescribed and not to share their medication with others. Inform patients about the potential side effects and the importance of adhering to follow-up appointments for monitoring purposes.

Sleep Aid