{"id":208,"date":"2025-08-08T17:44:44","date_gmt":"2025-08-08T17:44:44","guid":{"rendered":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/?post_type=product&p=208"},"modified":"2025-09-05T08:26:47","modified_gmt":"2025-09-05T08:26:47","slug":"metoclopramide","status":"publish","type":"product","link":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/product\/metoclopramide\/","title":{"rendered":"Metoclopramide"},"content":{"rendered":"

Medication Overview<\/h1>\n

Metoclopramide is a prescription medication primarily used to treat various conditions related to nausea and vomiting. It is a prokinetic agent<\/a> that helps in the management of gastroparesis and symptoms caused by delayed gastric emptying. It increases the movement of the stomach and intestines, facilitating a more efficient digestion process.<\/p>\n

Brand Names<\/h2>\n

Metoclopramide is marketed under various brand names, including Reglan, Metozolv ODT, and Gimoti. These brands may offer the drug in different forms such as tablets, orally disintegrating tablets, and nasal sprays.<\/p>\n

Mechanism of Action<\/h3>\n

Metoclopramide works by blocking dopamine receptors in the brain and gastrointestinal tract. This action enhances the response of the upper digestive tract muscle to acetylcholine, resulting in increased gastric emptying and intestinal transit. In addition, it also acts on the central nervous system to reduce feelings of nausea.<\/p>\n

Metoclopramide is indicated for the treatment of gastroesophageal reflux disease (GERD) when other treatments have failed. It is also used to prevent nausea and vomiting associated with chemotherapy, radiation therapy, and surgery. Furthermore, it is employed in managing diabetic gastroparesis, a condition where the stomach cannot empty food normally.<\/p>\n

The typical adult dose for gastroparesis is 10 mg administered 30 minutes before meals and at bedtime. For treating GERD, the recommended dosage is usually 10-15 mg taken four times daily. Dosages may vary according to the specific condition being treated and the patient’s response to the medication. The duration of therapy is typically no longer than 12 weeks to minimize the risk of side effects.<\/p>\n

Metoclopramide is available in multiple forms\u00e2\u0080\u0094oral tablets, orally disintegrating tablets, and injectable solutions. Oral tablets should be swallowed whole with water, while orally disintegrating tablets should be allowed to dissolve on the tongue. The injectable form is usually administered by a healthcare provider in a clinical setting.<\/p>\n

Metoclopramide is metabolized in the liver and excreted primarily through the kidneys via urine. Its half-life ranges between 5 to 6 hours in healthy individuals, but may be extended in people with renal impairment, necessitating dose adjustments.<\/p>\n

Metoclopramide can interact with several medications, including antipsychotics, anti-Parkinson agents, and certain antidepressants such as SSRIs<\/a>. The drug also has the potential to amplify the sedative<\/a> effects of alcohol and other central nervous system depressants. Therefore, it is essential to inform your healthcare provider about all the medications you are taking.<\/p>\n

Common side effects of Metoclopramide include drowsiness, fatigue, and restlessness. Additionally, some patients may experience headaches, digestive disturbances, or trouble sleeping. Most side effects are mild and tend to diminish with continued use.<\/p>\n

Serious side effects can occur and may include tardive dyskinesia, a condition involving involuntary, repetitive body movements. Neuroleptic<\/a> malignant syndrome, characterized by fever, muscle rigidity, and autonomic dysfunction, is another rare but critical condition. Immediate medical attention is required if any serious side effects manifest.<\/p>\n

Metoclopramide is contraindicated in individuals with a history of tardive dyskinesia or other movement disorders. It should not be used in patients with gastrointestinal bleeding, mechanical obstruction, or perforation. Additionally, it is contraindicated in individuals with pheochromocytoma due to the risk of severe hypertension.<\/p>\n

Dosage adjustments are required for elderly patients and those with renal impairment due to the increased risk of side effects. Pregnant and breastfeeding women should use Metoclopramide only if the potential benefits outweigh the potential risks, as it can pass into breast milk and may affect the infant.<\/p>\n

Store Metoclopramide at room temperature, away from excessive moisture and heat. Keep it in its original container and out of the reach of children. Ensure the bottle or packaging is tightly sealed when not in use to maintain its efficacy.<\/p>\n

If you miss a dose of Metoclopramide, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your normal dosing schedule. Do not double up on doses to make up for a missed one, as this increases the risk of adverse effects.<\/p>\n","protected":false},"excerpt":{"rendered":"

Metoclopramide’s active ingredient is called metoclopramide hydrochloride. It is also known by brand names like Reglan and Maxolon. This medication is used to treat nausea, vomiting, and slow stomach emptying by helping to move food through the digestive tract.<\/p>\n

Metoclopramide Price Update<\/h2>\n

The price scale for Metoclopramide typically fluctuates between \u00a30.46 and \u00a30.69 per pills. Factors such as packaging dimensions and active ingredient ratio (60 or 360 mg) come into play.<\/p>\n","protected":false},"featured_media":238,"comment_status":"open","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[247],"product_tag":[],"class_list":{"0":"post-208","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-gastrointestinal","7":"desktop-align-left","8":"tablet-align-left","9":"mobile-align-left","11":"first","12":"instock","13":"shipping-taxable","14":"product-type-external"},"_links":{"self":[{"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/product\/208","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/comments?post=208"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/media\/238"}],"wp:attachment":[{"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/media?parent=208"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/product_brand?post=208"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/product_cat?post=208"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/product_tag?post=208"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}