{"id":216,"date":"2025-08-26T04:47:14","date_gmt":"2025-08-26T04:47:14","guid":{"rendered":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/?post_type=product&p=216"},"modified":"2025-09-05T08:26:40","modified_gmt":"2025-09-05T08:26:40","slug":"protonix","status":"publish","type":"product","link":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/product\/protonix\/","title":{"rendered":"Protonix"},"content":{"rendered":"

Medication Guide: Protonix<\/h1>\n

Generic Name<\/h2>\n

Pantoprazole sodium.<\/p>\n

Drug Class<\/h2>\n

Proton pump inhibitor (PPI).<\/p>\n

Formulations Available<\/h2>\n

Delayed-release tablets (20mg and 40mg) and oral suspension.<\/p>\n

Mechanism of Action<\/h2>\n

Pantoprazole inhibits the H+\/K+ ATPase enzyme system at the secretory surface of gastric parietal cells, blocking the final step in acid production.<\/p>\n

Primary Uses<\/h2>\n

Protonix is prescribed for the treatment of gastroesophageal reflux disease (GERD), erosive esophagitis, and pathological hypersecretory conditions including Zollinger-Ellison syndrome.<\/p>\n

Administration Guidelines<\/h2>\n

Administer 40mg orally once daily, at least 30 minutes before a meal. For the oral suspension, mix with apple juice or applesauce, consume immediately.<\/p>\n

Duration of Therapy<\/h2>\n

Treatment duration varies but typically ranges from 4 to 8 weeks. For maintenance therapy, longer durations may be prescribed.<\/p>\n

Contraindications<\/h2>\n

Protonix is contraindicated in patients with known hypersensitivity to any component of the formulation or to substituted benzimidazoles.<\/p>\n

Adverse Reactions<\/h2>\n

Common side effects include headache, diarrhea, nausea, abdominal pain, vomiting, flatulence, dizziness, and arthralgia. Serious adverse reactions include Clostridium difficile-associated diarrhea and vitamin B12 deficiency with long-term use.<\/p>\n

Drug Interactions<\/h2>\n

Pantoprazole may interfere with drugs requiring an acidic pH for absorption. It may also interact with warfarin<\/a>, methotrexate, and antiretroviral drugs.<\/p>\n

Monitoring Requirements<\/h2>\n

Monitor for relief of symptoms, adverse reactions, and lab tests like liver enzymes, particularly in prolonged treatment durations. Periodic assessment of renal function is advisable.<\/p>\n

Special Populations<\/h2>\n

In patients with severe liver impairment, dose reduction may be necessary. In elderly patients, cautious use is advised due to a higher frequency of side effects. Pediatric use for short-term treatment of GERD and erosive esophagitis is recommended in children aged 5 years and older.<\/p>\n

Storage Instructions<\/h2>\n

Store delayed-release tablets and oral suspension packets at room temperature, between 20\u00c2\u00b0C to 25\u00c2\u00b0C (68\u00c2\u00b0F to 77\u00c2\u00b0F). Protect from moisture and light.<\/p>\n

Overdosage Information<\/h2>\n

In case of overdose, symptoms may include confusion, drowsiness, blurred vision, tachycardia, nausea, vomiting, and sweating. Treatment is symptomatic and supportive.<\/p>\n

Pharmacokinetics<\/h2>\n

Pantoprazole is absorbed after oral administration with peak plasma concentrations occurring approximately 2.5 hours post-dose. Its bioavailability is about 77%. It is primarily metabolized in the liver, with a half-life of about 1 hour.<\/p>\n

Patient Counseling Points<\/h2>\n

Inform patients to take Protonix exactly as prescribed, preferably early in the morning before meals. Emphasize the importance of not splitting, crushing, or chewing the tablets. Advise patients to report severe, persistent side effects, and to inform healthcare providers about all concurrent medication usage, including over-the-counter drugs and supplements.<\/p>\n","protected":false},"excerpt":{"rendered":"

Protonix is a medication with the active ingredient pantoprazole. It is also known by the generic name pantoprazole and the brand names Protonix IV and Pantoloc. Protonix is used to reduce the amount of acid in the stomach, which helps treat conditions like GERD (gastroesophageal reflux disease) and stomach ulcers.<\/p>\n

Protonix Price<\/h2>\n

Protonix costs between \u00a30.3 and \u00a30.75 per pills. Depending on the size of the pack and the number of tablets inside (60 or 360 mg).<\/p>\n","protected":false},"featured_media":246,"comment_status":"open","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[247],"product_tag":[],"class_list":{"0":"post-216","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-gastrointestinal","7":"desktop-align-left","8":"tablet-align-left","9":"mobile-align-left","11":"first","12":"instock","13":"shipping-taxable","14":"product-type-external"},"_links":{"self":[{"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/product\/216","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/comments?post=216"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/media\/246"}],"wp:attachment":[{"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/media?parent=216"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/product_brand?post=216"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/product_cat?post=216"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/product_tag?post=216"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}