{"id":318,"date":"2025-08-16T16:14:10","date_gmt":"2025-08-16T16:14:10","guid":{"rendered":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/?post_type=product&#038;p=318"},"modified":"2025-09-05T08:26:44","modified_gmt":"2025-09-05T08:26:44","slug":"prinivil","status":"publish","type":"product","link":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/product\/prinivil\/","title":{"rendered":"Prinivil"},"content":{"rendered":"<h2>Generic Name<\/h2>\n<p><a href=\"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/product\/lisinopril\/\" data-internallinksmanager029f6b8e52c=\"59\" title=\"Lisinopril\">Lisinopril<\/a>.<\/p>\n<h2>Therapeutic Class<\/h2>\n<p>Angiotensin-Converting Enzyme (ACE) Inhibitor.<\/p>\n<h2>Indications<\/h2>\n<p>Used to treat high blood pressure (hypertension), heart failure, and to improve survival after heart attack.<\/p>\n<h2>Dosage Forms<\/h2>\n<p>Available in oral tablet form in strengths of 2.5 mg, 5 mg, 10 mg, 20 mg, 30 mg, and 40 mg; also available as an oral solution.<\/p>\n<h2>Administration<\/h2>\n<p>Administered orally once daily, with or without food.<\/p>\n<h2>Mechanism of Action<\/h2>\n<p>Lisinopril works by inhibiting the angiotensin-converting enzyme (ACE), which leads to decreased levels of angiotensin II and decreased aldosterone production, resulting in vasodilation and reduced blood pressure.<\/p>\n<h2>Pharmacokinetics<\/h2>\n<p>It has an onset of action within 1 hour, peak effect in 6-7 hours, and duration of effect lasts approximately 24 hours. Lisinopril is not metabolized and is excreted unchanged primarily in urine.<\/p>\n<h2>Recommended Dosage<\/h2>\n<p>Hypertension: Starting dose is 10 mg once daily, with maintenance doses ranging from 20 to 40 mg daily. Heart failure: Starting dose is 5 mg once daily, with a maintenance dose from 20 to 40 mg daily. Post-myocardial infarction: Starting dose is 5 mg once daily, followed by 10 mg daily for six weeks.<\/p>\n<h2>Initial Monitoring<\/h2>\n<p>Monitor blood pressure, renal function (serum creatinine), and serum potassium levels before and during treatment.<\/p>\n<h2>Adverse Effects<\/h2>\n<p>Common side effects include cough, dizziness, headache, fatigue, and nausea. Serious side effects can include angioedema, hyperkalemia, severe hypotension, and renal impairment.<\/p>\n<h2>Drug Interactions<\/h2>\n<p>Concomitant use of potassium supplements or <a href=\"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/product\/torsemide\/\" data-internallinksmanager029f6b8e52c=\"221\" title=\"Torsemide\">potassium-sparing<\/a> diuretics may increase the risk of hyperkalemia. Use with diuretics may cause excessive reduction in blood pressure. Nonsteroidal <a href=\"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/product\/differin\/\" data-internallinksmanager029f6b8e52c=\"48\" title=\"Differin\">anti-inflammatory<\/a> drugs (NSAIDs) may reduce the <a href=\"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/product\/lopressor\/\" data-internallinksmanager029f6b8e52c=\"18\" title=\"Lopressor\">antihypertensive<\/a> efficacy of lisinopril.<\/p>\n<h2>Special Populations<\/h2>\n<p>Use caution in patients with renal impairment; dosage adjustment may be necessary. Not recommended for use during pregnancy due to potential risk to the fetus. In lactating women, the effect on breastfed infants is unknown; use with caution.<\/p>\n<h2>Contraindications<\/h2>\n<p>Contraindicated in patients with a history of angioedema related to previous ACE inhibitor therapy, hypersensitivity to lisinopril or any component of the formulation, and hereditary or idiopathic angioedema.<\/p>\n<h2>Storage Conditions<\/h2>\n<p>Store at controlled room temperature, between 15\u00c2\u00b0C to 30\u00c2\u00b0C (59\u00c2\u00b0F to 86\u00c2\u00b0F). Protect from moisture and light.<\/p>\n<h2>Patient Counseling Points<\/h2>\n<p>Inform patients about the potential for dizziness, especially when starting therapy. Advise them to avoid activities requiring mental alertness until they know how the medication affects them. Teach patients to report any signs of swelling, especially in the face or throat, immediately. Inform them to maintain adequate hydration and inform their healthcare provider of other medications or supplements they are taking.<\/p>\n<h2>Renal Protection<\/h2>\n<p>May provide protective effects on the kidneys in patients with diabetes and hypertension by reducing glomerular hypertension and proteinuria.<\/p>\n<h2>Alternative Treatments<\/h2>\n<p>Include other antihypertensive agents such as ARBs (angiotensin II receptor blockers), calcium channel blockers, and thiazide diuretics.<\/p>\n<h2>Generic Availability<\/h2>\n<p>Available as a generic medication, which may be more cost-effective for patients compared to the brand-name equivalent.<\/p>\n<h2>Impact on Elderly<\/h2>\n<p>In elderly patients, increased sensitivity to the blood pressure-lowering effects may be observed, necessitating careful dosage adjustments and monitoring.<\/p>\n<h2>Pediatric Use<\/h2>\n<p>Approved for use in pediatric patients 6 years and older for hypertension, but safety and efficacy in children under 6 have not been established.<\/p>\n<h2>Brand Name<\/h2>\n<p>Prinivil is the brand name of lisinopril as marketed by Merck &amp; Co.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Prinivil, also known as lisinopril, is a medication used to treat high blood pressure and heart failure. Its active ingredient is lisinopril. It also goes by the names Zestril and Qbrelis. It helps relax blood vessels so blood can flow more easily.<\/p>\n<h2>Prinivil Price Update<\/h2>\n<p>The Prinivil price is approximately \u00a30.16 &#8211; \u00a31.37 per pills. It depends on the pack size and the amount of active ingredient (30 or 360 mg).<\/p>\n","protected":false},"featured_media":347,"comment_status":"open","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[297],"product_tag":[],"class_list":{"0":"post-318","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-heart-disease","7":"desktop-align-left","8":"tablet-align-left","9":"mobile-align-left","11":"first","12":"instock","13":"shipping-taxable","14":"product-type-external"},"_links":{"self":[{"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/product\/318","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/comments?post=318"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/media\/347"}],"wp:attachment":[{"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/media?parent=318"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/product_brand?post=318"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/product_cat?post=318"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/product_tag?post=318"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}