{"id":329,"date":"2025-08-27T23:25:41","date_gmt":"2025-08-27T23:25:41","guid":{"rendered":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/?post_type=product&#038;p=329"},"modified":"2025-09-05T08:26:40","modified_gmt":"2025-09-05T08:26:40","slug":"avapro","status":"publish","type":"product","link":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/product\/avapro\/","title":{"rendered":"Avapro"},"content":{"rendered":"<h1>Avapro Medication Guide<\/p>\n<h2>Active Ingredient<\/h2>\n<p>Avapro contains the active ingredient irbesartan. Irbesartan is an angiotensin II receptor antagonist that helps to relax blood vessels by blocking the action of angiotensin II, a chemical in the body that tightens blood vessels.<\/p>\n<h2>Pharmacological Class<\/h2>\n<p>Avapro belongs to a class of drugs known as angiotensin II receptor blockers (ARBs). ARBs are primarily used in the management of hypertension and diabetic nephropathy in patients with <a href=\"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/product\/rybelsus-semaglutide\/\" data-internallinksmanager029f6b8e52c=\"215\" title=\"Rybelsus (semaglutide)\">type 2 diabetes<\/a>.<\/p>\n<h2>Indications for Use<\/h2>\n<p>Avapro is primarily prescribed for the treatment of hypertension (high blood pressure). Additionally, it is indicated for the treatment of diabetic nephropathy in patients with type 2 diabetes and hypertension.<\/p>\n<h2>Mechanism of Action<\/h2>\n<p>Avapro works by blocking the binding of angiotensin II to its receptor, which results in the dilation of blood vessels and a reduction in blood pressure. This action helps to improve blood flow and reduces the workload on the heart.<\/p>\n<h2>Dosage Forms<\/h2>\n<p>Avapro is available in oral tablet form. The tablets are produced in various strengths, including 75 mg, 150 mg, and 300 mg. Each tablet is film-coated for easy swallowing.<\/p>\n<h2>Recommended Dosage<\/h2>\n<p>The usual starting dose for treating hypertension is 150 mg once daily. If necessary, the dose may be increased to 300 mg once daily. For diabetic nephropathy, the recommended dose is 300 mg once daily. Dosage adjustments should be made based on patient response and clinical condition.<\/p>\n<h2>Administration Instructions<\/h2>\n<p>Avapro should be taken once daily, with or without food. Consistency in the time of administration should be maintained to ensure optimal efficacy. Swallow the tablet whole with a glass of water.<\/p>\n<h2>Renal Impairment Considerations<\/h2>\n<p>For patients with renal impairment, dose adjustments are generally not necessary. However, monitoring of renal function is recommended in patients with severe renal impairment or end-stage renal disease.<\/p>\n<h2>Hepatic Impairment Adjustments<\/h2>\n<p>Patients with mild to moderate hepatic impairment do not typically require a dosage adjustment. However, it is important to monitor liver function tests periodically.<\/p>\n<h2>Drug Interactions<\/h2>\n<p>Concurrent use with other <a href=\"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/product\/lopressor\/\" data-internallinksmanager029f6b8e52c=\"18\" title=\"Lopressor\">antihypertensive<\/a> agents may enhance the blood pressure-lowering effect. Avoid potassium supplements or <a href=\"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/product\/torsemide\/\" data-internallinksmanager029f6b8e52c=\"221\" title=\"Torsemide\">potassium-sparing<\/a> diuretics, as these may increase the risk of hyperkalemia. Inform your healthcare provider about all medications, including over-the-counter drugs, and herbal supplements.<\/p>\n<h2>Storage Conditions<\/h2>\n<p>Store Avapro tablets at a temperature between 20\u00c2\u00b0C and 25\u00c2\u00b0C (68\u00c2\u00b0F and 77\u00c2\u00b0F). Protect from light and moisture. Keep the medication in its original container and out of reach of children.<\/p>\n<h2>Adverse Reactions<\/h2>\n<p>Common adverse reactions include dizziness, fatigue, and gastrointestinal disturbances such as nausea and diarrhea. Rare but serious side effects include hyperkalemia, renal dysfunction, and angioedema.<\/p>\n<h2>Pregnancy Category<\/h2>\n<p>Avapro is classified as pregnancy category D. It is contraindicated during pregnancy due to the risk of fetal toxicity. Women of childbearing potential should use effective contraception while taking this medication.<\/p>\n<h2>Breastfeeding Precautions<\/h2>\n<p>It is not known whether irbesartan is excreted in human milk. Due to potential adverse effects on the nursing infant, a decision should be made whether to discontinue nursing or to discontinue the drug.<\/p>\n<h2>Pediatric Use<\/h2>\n<p>The safety and efficacy of Avapro in pediatric patients have not been established. Therefore, it is not recommended for use in children under 18 years of age.<\/p>\n<h2>Geriatric Considerations<\/h2>\n<p>In clinical studies, no overall differences in effectiveness or safety were observed between elderly and younger patients. However, greater sensitivity of some older individuals cannot be ruled out.<\/p>\n<h2>Overdose Management<\/h2>\n<p>In the event of an overdose, symptomatic and supportive treatment should be provided. Activated charcoal may be considered to reduce absorption. Hemodialysis does not significantly remove irbesartan from the bloodstream.<\/p>\n<h2>Brand and Generic Availability<\/h2>\n<p>Avapro is the brand name for irbesartan. Generic versions are available and may be prescribed as an alternative depending on formulary considerations and patient preference.<\/p>\n<h2>Manufacturer Information<\/h2>\n<p>Avapro is manufactured by Sanofi-Aventis, a global pharmaceutical company known for its innovative treatments and rigorous quality control standards.<\/p>\n<h2>Regulatory Approval<\/h2>\n<p>Avapro was approved by the U.S. Food and Drug Administration (FDA) for the treatment of hypertension and diabetic nephropathy in type 2 diabetic patients.<\/p>\n<h2>Patient Counseling Information<\/h2>\n<p>Patients should be informed about the nature of their condition and the importance of adherence to the prescribed regimen. Educate them on the potential side effects and the need for regular monitoring of blood pressure, renal function, and electrolytes.<\/p>\n<\/h1>\n","protected":false},"excerpt":{"rendered":"<p>Avapro, also known as irbesartan, is a medication used to treat high blood pressure. The active ingredient in Avapro is irbesartan. It is also called an angiotensin II receptor blocker (ARB), which helps to relax blood vessels.<\/p>\n<h2>Avapro Price Details<\/h2>\n<p>The pricing structure for Avapro is set between \u00a30.57 and \u00a31.3 for every pills. It&#8217;s reflective of the size of the packaging and ingredient concentration (30 or 360 mg).<\/p>\n","protected":false},"featured_media":358,"comment_status":"open","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[293],"product_tag":[],"class_list":{"0":"post-329","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-diabetes","7":"desktop-align-left","8":"tablet-align-left","9":"mobile-align-left","11":"first","12":"instock","13":"shipping-taxable","14":"product-type-external"},"_links":{"self":[{"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/product\/329","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/comments?post=329"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/media\/358"}],"wp:attachment":[{"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/media?parent=329"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/product_brand?post=329"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/product_cat?post=329"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/product_tag?post=329"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}