{"id":547,"date":"2025-08-11T20:52:27","date_gmt":"2025-08-11T20:52:27","guid":{"rendered":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/?post_type=product&p=547"},"modified":"2025-09-05T08:26:46","modified_gmt":"2025-09-05T08:26:46","slug":"dapoxetine","status":"publish","type":"product","link":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/product\/dapoxetine\/","title":{"rendered":"Dapoxetine"},"content":{"rendered":"

Medication Description and Usage<\/h3>\n

Dapoxetine is a short-acting selective serotonin reuptake<\/a> inhibitor (SSRI) formulated to treat premature ejaculation in men. It increases serotonin levels, leading to delayed ejaculation.<\/p>\n

Pharmacokinetics and Dynamics<\/h3>\n

After oral administration, dapoxetine is rapidly absorbed, reaching peak plasma concentrations within 1-2 hours. It has a half-life of approximately 19 hours, and its metabolization occurs primarily in the liver via CYP2D6 and CYP3A4 enzymes.<\/p>\n

Indicated Populations<\/h3>\n

Dapoxetine is intended for use in adult men aged 18-64 years who experience premature ejaculation. It should not be prescribed to individuals under 18 or over 65 years of age.<\/p>\n

Administration Guidelines<\/h3>\n

Dapoxetine should be taken 1-3 hours before anticipated sexual activity. Tablets are swallowed whole with water and can be taken with or without food. A maximum of one dose per day is advised.<\/p>\n

Dosage Information<\/h3>\n

The recommended starting dose is 30 mg. Depending on individual response and tolerability, the dose may be increased to 60 mg. Adjustments should only be made with professional healthcare guidance.<\/p>\n

Mechanism of Action<\/h3>\n

Dapoxetine works by inhibiting the serotonin transporter, increasing serotonin’s action in the synaptic cleft. This postpones ejaculatory latency by enhancing the control over ejaculation.<\/p>\n

Common Side Effects<\/h3>\n

Patients may experience mild to moderate side effects, including nausea, dizziness, headache, and diarrhea. These effects are generally transient and decrease with continued use.<\/p>\n

Serious Side Effects<\/h3>\n

Though rare, severe adverse reactions such as syncope, mood changes, and serotonin syndrome may occur. Immediate medical consultation is required if any severe symptoms are noted.<\/p>\n

Drug Interactions<\/h3>\n

Dapoxetine interacts with monoamine oxidase inhibitors (MAOIs), thioridazine, and SSRIs<\/a>. Concurrent use with these medications can increase the risk of serotonin syndrome or serious cardiac arrhythmias.<\/p>\n

Alcohol Interaction<\/h3>\n

Consumption of alcohol while taking dapoxetine may enhance sedative<\/a> effects, leading to increased dizziness, syncope, and impaired judgment. Alcohol intake should be minimized.<\/p>\n

Renal and Hepatic Impairment<\/h3>\n

Patients with severe renal impairment should avoid dapoxetine. Those with mild to moderate impairment must use it with caution. Hepatic impairment also affects its metabolism, requiring dosage adjustments.<\/p>\n

Contraindications<\/h3>\n

Dapoxetine is contraindicated in patients with significant heart diseases, including heart failure and conduction abnormalities. It should not be used by those with hypersensitivity to dapoxetine or its excipients.<\/p>\n

Special Precautions<\/h3>\n

Prescribers should evaluate the patient\u00e2\u0080\u0099s psychiatric history, as dapoxetine can exacerbate conditions such as depression or bipolar disorder<\/a>. Regular monitoring is essential for vulnerable individuals.<\/p>\n

Pregnancy and Lactation<\/h3>\n

Dapoxetine is not indicated for use in women. There is insufficient data on its safety regarding pregnancy and lactation, thus it should not be used by pregnant or breastfeeding women.<\/p>\n

Storage Conditions<\/h3>\n

Store dapoxetine at room temperature, away from direct light and moisture. Keep it in its original packaging until use, and ensure it is out of reach of children.<\/p>\n

Missed Dose Instructions<\/h3>\n

Dapoxetine is taken as needed to manage premature ejaculation, so missed dose instructions are not applicable. Do not double the dose if the next scheduled dose is missed.<\/p>\n

Overdose Management<\/h3>\n

In the event of an overdose, symptomatic treatment should be administered. Supportive measures such as monitoring cardiac and respiratory functions may be necessary.<\/p>\n

Special Population Use<\/h3>\n

For elderly patients over 65, caution is advised due to increased susceptibility to side effects. Renal and hepatic function tests may be required to tailor the appropriate dosage regimen.<\/p>\n

Patient Counseling Information<\/h3>\n

Healthcare providers should counsel patients on the expected benefits and potential side effects of dapoxetine. Educate patients on the importance of adhering to the prescribed dosage and avoiding alcohol.<\/p>\n

Clinical Trial Data<\/h3>\n

Clinical trials have shown dapoxetine to significantly prolong ejaculation time compared to placebo. Participants reported improved control and satisfaction in their sexual experiences.<\/p>\n

Off-label Use<\/h3>\n

There is limited evidence supporting the off-label use of dapoxetine for conditions other than premature ejaculation. Prescribers should exercise caution and rely on clinical judgment when considering off-label uses.<\/p>\n

Peer-reviewed Studies<\/h3>\n

Numerous peer-reviewed studies confirm dapoxetine’s efficacy in treating premature ejaculation, demonstrating significant improvements in Intravaginal Ejaculatory Latency Time (IELT) and overall sexual function questionnaires.<\/p>\n","protected":false},"excerpt":{"rendered":"

Dapoxetine is a medication with the active ingredient dapoxetine hydrochloride. It is also known by alternative names such as Priligy and Westoxetin. This medication is primarily used to treat premature ejaculation in men, helping to improve control over the timing of ejaculation.<\/p>\n

Dapoxetine Price<\/h2>\n

The standard rate for Dapoxetine oscillates between \u00a30.77 and \u00a33.93 for each pills. It\u2019s contingent on the package dimensions and ingredient intensity (10 or 360 mg).<\/p>\n","protected":false},"featured_media":558,"comment_status":"open","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[246],"product_tag":[],"class_list":{"0":"post-547","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-mens-health","7":"desktop-align-left","8":"tablet-align-left","9":"mobile-align-left","11":"first","12":"instock","13":"shipping-taxable","14":"product-type-external"},"_links":{"self":[{"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/product\/547","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/comments?post=547"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/media\/558"}],"wp:attachment":[{"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/media?parent=547"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/product_brand?post=547"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/product_cat?post=547"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/product_tag?post=547"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}