{"id":82,"date":"2025-08-16T07:59:25","date_gmt":"2025-08-16T07:59:25","guid":{"rendered":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/?post_type=product&p=82"},"modified":"2025-09-05T08:26:44","modified_gmt":"2025-09-05T08:26:44","slug":"naltrexone","status":"publish","type":"product","link":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/product\/naltrexone\/","title":{"rendered":"Naltrexone"},"content":{"rendered":"

Medication Name<\/h1>\n

Naltrexone<\/p>\n

Active Ingredient<\/h2>\n

Naltrexone hydrochloride.<\/p>\n

Drug Classification<\/h2>\n

Opioid antagonist.<\/p>\n

Physical Description<\/h2>\n

Typically available as tablets or injectable solution.<\/p>\n

Intended Uses<\/h2>\n

Treatment of alcohol dependence and opioid dependence.<\/p>\n

Mechanism of Action<\/h2>\n

Blocks opioid receptors in the brain, reducing the effects of alcohol and opioids.<\/p>\n

Dosage Forms<\/h2>\n

Available in oral tablets and injectable formulations.<\/p>\n

Typical Dosage<\/h2>\n

For alcohol dependence: 50 mg orally per day. For opioid dependence: 380 mg intramuscularly once a month.<\/p>\n

Administration Guidelines<\/h2>\n

Oral tablets should be taken with water. The injectable form must be administered by a healthcare provider.<\/p>\n

Pharmacokinetics<\/h2>\n

Oral bioavailability approximately 5-40%. Peak plasma levels in about 1 hour post-oral ingestion.<\/p>\n

Metabolism<\/h2>\n

Mainly metabolized in the liver to 6-beta-naltrexol.<\/p>\n

Excretion<\/h2>\n

Primarily excreted in urine, with some excretion in bile.<\/p>\n

Precautionary Screening<\/h2>\n

Patients should be opioid-free for 7-10 days before starting naltrexone therapy to avoid withdrawal symptoms.<\/p>\n

Potential Drug Interactions<\/h2>\n

May interact with medications that affect the liver, opioid analgesics, and certain psychiatric medications.<\/p>\n

Contraindications<\/h2>\n

Contraindicated in patients currently on opioid analgesics, with acute hepatitis, or severe liver failure.<\/p>\n

Common Side Effects<\/h2>\n

May include nausea, headaches, dizziness, fatigue, and anxiety.<\/p>\n

Serious Side Effects<\/h2>\n

Rare but may include liver damage, depression, and allergic reactions.<\/p>\n

Monitoring Requirements<\/h2>\n

Liver function tests before and during treatment. Psychological evaluation to monitor for depression.<\/p>\n

Dosing Adjustments<\/h2>\n

Adjustments may be necessary based on liver function and patient response. Consult with healthcare provider.<\/p>\n

Missed Dose Protocol<\/h2>\n

If a dose is missed, take it as soon as remembered unless it is close to the time for the next dose.<\/p>\n

Storage Instructions<\/h2>\n

Store at room temperature, away from moisture and heat. Keep out of reach of children.<\/p>\n

Overdose Management<\/h2>\n

Contact emergency services immediately. Symptoms may include severe nausea and vomiting.<\/p>\n

Pregnancy and Breastfeeding<\/h2>\n

Not recommended during pregnancy or breastfeeding unless the benefits outweigh the risks. Consult healthcare provider.<\/p>\n

Patient Counseling<\/h2>\n

Inform patients about the potential for liver damage and the importance of regular liver function tests.<\/p>\n

Duration of Therapy<\/h2>\n

Varies depending on individual patient needs and response. Long-term therapy may be necessary.<\/p>\n

Dispensing Instructions<\/h2>\n

Ensure the correct form of medication is provided (tablet or injectable). Verify dosage instructions with patient.<\/p>\n

Patient Assistance Programs<\/h2>\n

Some pharmaceutical companies offer financial assistance programs to help cover the cost of naltrexone.<\/p>\n

Alternative Treatments<\/h2>\n

Alternative medications for alcohol and opioid dependence include acamprosate, methadone, and buprenorphine.<\/p>\n

Physician Collaboration<\/h2>\n

Close collaboration with prescribing physician is essential to ensure safe and effective use.<\/p>\n

Legal Considerations<\/h2>\n

Classified as a non-controlled substance but may be subject to prescription regulations.<\/p>\n

Research Studies<\/h2>\n

Clinical studies indicate efficacy in reducing alcohol and opioid consumption when used as part of a comprehensive treatment program.<\/p>\n

Patient Education<\/h2>\n

Educate patients about the importance of adherence to treatment and the potential consequences of missing doses.<\/p>\n

Insurance Coverage<\/h2>\n

Most insurance plans cover naltrexone, but prior authorization may be required.<\/p>\n

Comparative Efficacy<\/h2>\n

Studies show naltrexone is effective but may be less effective than some opioid agonist therapies for opioid dependence.<\/p>\n

Withdrawal Symptoms<\/h2>\n

Not commonly associated with withdrawal symptoms but may precipitate withdrawal in those currently using opioids.<\/p>\n","protected":false},"excerpt":{"rendered":"

Naltrexone is a medicine with the active ingredient Naltrexone hydrochloride. It is also known by other names like Revia and Vivitrol. This medication is used to help people stop taking drugs or drinking alcohol by blocking the effects these substances have on the brain.<\/p>\n

Naltrexone Price Analysis<\/h2>\n

The cost of the Naltrexone varies from \u00a35.41 to \u00a37.12 per pills. It depends on the size of the pack and the amount of active ingredient (10 or 90 mg).<\/p>\n","protected":false},"featured_media":110,"comment_status":"open","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[151],"product_tag":[],"class_list":{"0":"post-82","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-other","7":"desktop-align-left","8":"tablet-align-left","9":"mobile-align-left","11":"first","12":"instock","13":"shipping-taxable","14":"product-type-external"},"_links":{"self":[{"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/product\/82","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/comments?post=82"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/media\/110"}],"wp:attachment":[{"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/media?parent=82"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/product_brand?post=82"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/product_cat?post=82"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/www.hamptonhealthpharmacy.co.uk\/online\/wp-json\/wp\/v2\/product_tag?post=82"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}