Desyrel contains the active ingredient trazodone. It is also known by the names Oleptro and Trittico. Desyrel is commonly used to treat depression and can help with anxiety and insomnia. It works by balancing certain chemicals in the brain.
The price spectrum for Desyrel is set between £0.3 and £0.9 per pills. It’s mainly based on the pack’s volume and the strength of its active ingredients (30 or 360 mg).
Desyrel (generic name: trazodone) is an antidepressant medication used to treat major depressive disorder. It may also be prescribed for insomnia and other conditions as deemed appropriate by a healthcare provider. The medication is available in tablet form and should be taken as directed by a physician.
Desyrel belongs to a class of medications known as serotonin antagonist and reuptake inhibitors (SARIs). This class of drugs functions by affecting neurotransmitters in the brain, specifically increasing serotonin levels, which can help improve mood.
Desyrel works by inhibiting the reuptake of serotonin in the brain and antagonizing certain serotonin receptors. This dual action helps to increase the levels of serotonin available in the synaptic cleft, thereby enhancing mood regulation.
Desyrel is primarily indicated for the treatment of major depressive disorder. It may also be prescribed off-label for conditions such as anxiety disorders, chronic pain, and insomnia.
The usual starting dose of Desyrel for adults is 150 mg per day, divided into several doses. This dosage may be increased by the healthcare provider based on the patient’s response and tolerance. Maximum dosage should not exceed 400 mg per day for outpatients and 600 mg per day for inpatients.
Desyrel should be taken orally with a glass of water, preferably after a meal or snack to decrease the risk of gastrointestinal side effects. It is advisable to take the larger portion of the daily dose at bedtime to minimize daytime drowsiness.
Common side effects of Desyrel include dizziness, drowsiness, dry mouth, headache, and blurred vision. Some patients may experience gastrointestinal issues such as nausea or constipation. It is important to report any severe or persistent symptoms to a healthcare provider.
Desyrel can interact with other medications affecting serotonin levels, such as selective serotonin reuptake inhibitors (SSRIs), monoamine oxidase inhibitors (MAOIs), and certain pain medications. Concurrent use with alcohol or other CNS depressants should be avoided due to increased risk of sedation.
Desyrel should be used with caution in elderly patients, as they may be more susceptible to side effects such as sedation and hypotension. Dosage adjustments may be required for patients with liver or kidney impairment. Pregnant or breastfeeding women should use this medication only if the potential benefits justify the potential risks to the fetus or infant.
Patients on Desyrel should be regularly monitored for signs of worsening depression or emerging suicidal thoughts, especially during the initial treatment period or when doses are changed. Periodic monitoring of liver and kidney function tests may also be warranted.
If a dose of Desyrel is missed, it should be taken as soon as the patient remembers. However, if it is almost time for the next dose, the missed dose should be skipped. Patients should not double doses to make up for a missed one.
Symptoms of Desyrel overdose may include extreme drowsiness, vomiting, and irregular heartbeats. In case of overdose, immediate medical attention is required. Management generally involves symptomatic and supportive care, as well as monitoring of cardiac and respiratory function.
Desyrel should be stored at room temperature, away from moisture and light. It should be kept in a tightly closed container and out of reach of children and pets.
Patients should be informed about the possible side effects and instructed to report any unusual or severe symptoms to their healthcare provider. They should be advised against operating heavy machinery or driving until they know how Desyrel affects them. Alcohol consumption should be limited while on this medication.