Voltaren is a medication that contains diclofenac as its active ingredient. It is also known by other names like Cataflam and Arthrotec. Voltaren is used to relieve pain and reduce inflammation in conditions such as arthritis or muscle injuries.
The common price range for Voltaren lies between £0.22 – £0.48 per pills. This range is subject to the size of the packaging and the potency of the contained ingredients (60 or 360 mg).
Voltaren contains diclofenac sodium as its active ingredient, a nonsteroidal anti-inflammatory drug (NSAID) used for reducing inflammation and pain.
Diclofenac inhibits cyclooxygenase-1 and cyclooxygenase-2 (COX-1 and COX-2) enzymes, which are involved in the synthesis of prostaglandins, thus reducing inflammation and pain.
Voltaren is indicated for the treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, and other inflammatory conditions. It is also used for acute pain and dysmenorrhea.
Voltaren is available in various formulations, including oral tablets, topical gels, and suppositories. Each formulation has specific dosage forms and strengths tailored to its route of administration.
The recommended starting oral dose for adults ranges from 50 to 150 mg per day, divided into multiple doses. For topical application, a specific amount of gel should be measured according to the condition being treated.
Oral Voltaren should be taken with food to minimize gastrointestinal discomfort. The topical gel should be applied to clean, dry skin and gently massaged until fully absorbed.
After oral administration, diclofenac is rapidly absorbed with peak plasma levels occurring within 1-2 hours. It is extensively metabolized in the liver and excreted in the urine and bile.
Voltaren is contraindicated in patients with known hypersensitivity to diclofenac, those who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs, and in patients with active gastrointestinal bleeding.
Concomitant use of Voltaren with other NSAIDs, anticoagulants, antiplatelet drugs, or selective serotonin reuptake inhibitors (SSRIs) may increase the risk of gastrointestinal bleeding and ulceration. Interaction with diuretics or antihypertensive drugs may reduce their effectiveness.
Patients with a history of cardiovascular disease, hypertension, renal impairment, or liver dysfunction should use Voltaren with caution and under close medical supervision. Periodic monitoring is advised during prolonged therapy.
Voltaren should be stored at room temperature, away from moisture and heat. Keep the medication out of reach of children and pets.
Common adverse effects include gastrointestinal disturbances such as nausea, vomiting, diarrhea, and abdominal pain. Other side effects may include headache, dizziness, and elevated liver enzymes.
In case of overdose, supportive measures including gastric lavage and administration of activated charcoal should be considered. Monitoring of renal and liver function is recommended. Symptomatic treatment must be initiated where necessary.
The safety and efficacy of Voltaren in pediatric patients have not been established. Use in this population is generally not recommended unless prescribed by a healthcare provider.
Voltaren should be avoided during the third trimester of pregnancy due to the risk of premature closure of the ductus arteriosus in the fetus. Use in the first and second trimesters only if the potential benefit justifies the potential risk to the fetus.
Diclofenac passes into breast milk in small amounts. Due to the potential risk of serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or discontinue the drug.
Elderly patients are at an increased risk for developing adverse reactions to NSAIDs, especially gastrointestinal bleeding and renal impairment. Dose adjustments and close monitoring may be necessary.
Periodic monitoring of blood pressure, renal function, liver enzymes, and complete blood count is recommended during long-term therapy with Voltaren. Regular follow-up helps in minimizing the risk of serious side effects.